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Dr. Yiling Fu

Areas of expertise

General: Cardiovascular and renal physiology

Specific: Mechanisms of the nonselective cation channel, TRPC6, in renal injury by diabetes and hypertension; contributions of tubuloglomerular feedback in hypertension; renal tubular ion-transport

Research methods

Genetically engineered mouse models

Chronically monitoring BP and HR in conscious rodents using implantable telemetry

Measurement of glomerular filtration rate and/or renal handling of substrates in conscious and anesthetized animals

Using micro-puncture to access single glomerular filtration rate and tubuloglomerular feedback in rodent kidneys.

Molecular, and biochemical assays (RT-PCR, Western Blot, IHC, ELISA, etc.)

Current project

The role of transient receptor potential cation channel 6 (TRPC6) in renal injury induced by diabetes and hypertension

The effect of transient receptor potential cation channel 6 (TRPC6) deficiency in obesity and metabolic dysfunction

For more information

• Biosketch
• Research summary
• Links to PubMed articles